"The groundwork of all happiness is health." - Leigh Hunt

What is Aspergillus, the fungus behind recent hospital deaths?

A typical mold has killed two people and left 4 others seriously sick at one in all Sydney's biggest hospitals.

Health authorities are investigating a cluster of fungal infections on the Royal Prince Alfred Hospital's transplant unit.

Six patients developed infection between October and December 2025, a typical mold present in soil, vegetation, dust and moist environments.

In an announcement, a hospital spokesperson suggested the mold could have been present at nearby construction sites, that are a part of the hospital's A$940 million redevelopment.

So what's it? And must you be concerned?

Is this a typical mold?

Yes, molds are a form of filamentous fungus, meaning they form long chains, and are commonly present in soil, vegetation, and wetlands.

This form of mold is frequently harmless to healthy people. But it could possibly cause a severe respiratory disease called aspergillosis. Aspergillosis is affected 250,000 people Worldwide

How can it hurt?

This form of mold produces airborne spores, which individuals can breathe into their lungs.

There, these spores could cause infection within the smallest chambers of the lungs. This is because they release toxins and enzymes. Damage to lung tissue. These spores can spread to other parts of the body, similar to the brain, kidneys, heart or skin, resulting in further infection.

Symptoms of infection include fever, cough and chest pain. You could have trouble respiratory or start coughing up blood. Can also cause skin and eye infections.



Who is probably the most vulnerable?

Our immune system can normally fight infection. But individuals with weakened immune systems a Too much risk the event of an infection.

They include People undergoing chemotherapy.corticosteroid treatment, or organ or stem cell transplants. Transplant patients are particularly vulnerable. This is because their immune system should be deliberately weakened to forestall their body from rejecting the transplanted organ. If they someway inhale the spores, the fungus can more easily take hold of their lungs.



Transplant patients could have dormant spores of their lungs Also causes infection When the eggs are activated. But health officials haven't indicated that it happened at a Sydney hospital.

one Major American studies Only 59% of organ transplant recipients and 25% of stem cell transplant patients were still alive one yr after developing invasive aspergillosis.

People with asthma can have allergies even when their immune system is healthy. And it could possibly cause severe allergic reactions in people. Initial conditiona genetic condition through which sticky mucus blocks their airways. People with other lung conditions similar to tuberculosis, influenza or COVID are also at increased risk of infection.

What are the treatment options?

will be treated with Antifungal medications similar to itraconazole and corticosteroids. This treatment is simpler after we detect the infection early.

But researchers have identified strains that do not reply to the sort of treatment. Antifungal resistance is due to this fact an urgent problem.

What else do I want to know?

Infections are relatively unusual in the final population. And they're rare in hospitals, where there are often wards and rooms. High performance particle airor HEPA, filters. These filters capture and take away potentially harmful particles from the air.

However, construction work can disturb the soil near or across the hospital, releasing large numbers of spores into the air. This increases the danger of clustering of infections in hospitals. It shouldn't be yet clear if this has happened on the Royal Prince Alfred Hospital.