A research team from the University of Freenburg, led by Bio Chemist Professor Dr. Oliver Inisal, has discovered how “Shetanna Protein II” protects Nitrogen Binding Enzyme from the damage. Protein may help to make nitrogenians use in biotechnology and thus reduce the quantity of artificial fertilizer used. The results have been published within the journal.
A small helper for larger tasks: an oxygen sensor protein protects the enzymetic machinery of biological nitrogen fixation from serious damage. Its use in biotechnology may help reduce the usage of artificial fertilizers in agriculture in the long run. A research team headed by Bio -Chemist and Pharmacy Professor Dr. Oliver Inisal, belonging to the Faculty of Chemistry and Pharmacy, and the middle of Biological Signaling Studies (BIOSS) on the University of Freewaburg, have found how the so -called Shaythana Protein II works. Scientists used the newly established crew electron microscopy in Ferberg. Their results are published within the journal
Nitrogen fertilizer is environmentally disturbing
Element nitrogen is an integral a part of all organisms. In agriculture, it is usually added as fertilizer to enable more production in the long term. However, the production and application of those fertilizers is causing problems when it comes to energy and environment. For years, there have been attempts to transmit natural nitrogen fixes to bacteria and Archeia into crops. Enzyme is chargeable for the nitrogenine nitrogen. One of essentially the most serious problems with the transfer of plants is that nitrogenis is extremely sensitive to environmental oxygen, which is produced by plants throughout the photo synthesis process.
Schita protein II enzymes forms a fancy with nitrogens.
The team's Philip Frank, Simon Ferberger and Dr. Lin Zhang, led by Professor Oliver Enliel, have now been capable of show how a small factor, a small element, increases the protein II, oxygen concentration. It then creates a fancy with two ingredients of nitrogenys in a short time, which protects them from oxidative damage. In this process, the activated Sheet Protein II ties very large nitrogens and its affiliated redcreattes, which form long festivals with each proteins, which cannot reach the energetic centers of oxygen nitrogens. As soon because the cells overcome this oxidative stress, complex dissolves, and the enzyme can resume its work.
Used in plant cells is comprehensible
Even if the nitrogens are produced directly within the plant cells, it is probably going that such short tension stages will occur repeatedly with the rise within the variety of oxygen. In the event of biotechnology use, the mutual production of small -shaped protein II can then help save widespread enzymes in its recent environment and maintain its work in plant cells. “The preparation of nitrogenians working in plants will begin a sample shift in green biotechnology, and this little protein can contribute decisively to make it possible,” says Esel.
- Prof. Dr. Oliver is a professor of biochemistry on the Faculty of Chemistry and Pharmacy and a member of the Center for Biological Signaling Studies (BIOSS) on the University of Freberg. Its research focuses on complex enzyme system structures, function and biogenses. Philip Frank, Simon Freberger and Dr. Lin Zhang Oliver are members of the Research Group.
- The project was provided by the European Union as a part of the Research Center 'Cellular Protein Machine' dynamic organization 'with the ERC Advanced Grant for Professor Dr. Oliver Icel and with the German Research Foundation (DFG).