A brand new study has found that a fungal infection has been shown to stimulate its own immune system of fruit bees to eliminate brain cells, leading to symptoms of neurodegection.
The article published today states that a fungus called a fungus has succeeded in mobilizing the natural force of the fly, which kills neuron and glyia within the brain, causing More than half of the bees die, in comparison with greater than half of the dies after seven days. About 50 days.
In the experiments conducted by a team of academics from Birmingham University, infection chambers faced fruit flies. After three days of exhibition, Fungus had infiltrated the blood brain and he enrolled within the principal brain.
Scientists found that fungus fly immune system agents are able to issuing two different reactions called toll receptors. The Toll -1 receptor mobilized the discharge of anti -microbial peptides (AMP), which tries to attack and kill pathogens. However, Fungus also incited Toll 1 to stimulate the preparation of one other molecule called Sirm, which suppresses the immune response and as a substitute kills brain cells.
Elvisia Headlago, a professor of neurogentics at Birmingham University and the creator of the research, said:
“We have shown a process how fungus developed the immune system to enter the brain. The fungus address is found through a receptor that performs a standard practice to bring natural immunity. But it may also mobilize an exception within the brain.
“The key to the immune process is the master of the so -called destruction of the anti -winter, which is the cause of the death of the cells in the brain. Enables the ability to activate the master of destroying the immune system of fruit flies and enables to defeat the total cells. Blood brain and start feeding brain cells. “
Dr. Deaneshu Singh, who worked on a PhD education at Birmingham University, and is now a post doctor at Manchester University, said:
“From an evolutionary viewpoint, these results highlight the continued arms race between hosts and pathogens, where the hosts enhance their immune procedures, while developing recent strategies to stop pathogen immunity.
“It is important to put pressure that cannot affect humans. Some have joined the hostess, so they will only affect special hosts that affect the species of many insects, but not by the stars. Impact the brain. “